Technician/Bio-engineer for single-cell sequencing

Leuven VIB-KU Leuven Center for Brain & Disease Research

25 Oct 2020

Leuven

VIB-KU Leuven Center for Brain & Disease Research

Stein Aerts Lab

Technical Support

1

Job description

The Laboratory of Computational Biology (www.aertslab.org) together with the Single-Cell Expertise Unit of the Center of Brain & Disease Research (CBD) are seeking an enthusiastic lab technician or (bio-)engineer to perform large-scale single-cell sequencing experiments. 

These assays will be performed in collaboration with the single-cell expertise unit and the Aerts lab, and with other researchers at the CBD. The assays include single-cell transcriptomics, single-cell epigenomics, single-cell multi-omics, and spatial omics assays. You will use both commercial platforms such as 10x Genomics, or in-house developed platforms including droplet microfluidics and robotic plate based setups. Depending on the profile and interest of the candidate, he/she can develop, optimise, and benchmark new single-cell assays, and make them available as a service. The job requires frequent interactions with researchers in Leuven, and broader in Flanders, contacts with Industry, and with clinicians at UZ Leuven hospital. 

The candidate will furthermore be trained in next-generation sequencing, to handle the entire pipeline from biological sample to sequencing and reporting. From March 2021 onwards, the successful candidate will become responsible for a large-scale Parkinson’s project, for which millions of single cells will be sequenced.

Profile

Required

  • Masters Degree in bio-engineering or other life science programs including biochemistry, biology, biomedical sciences, or related fields. Alternatively, the candidate may hold a professional bachelors degree, but with several years of experience in molecular biology.
  • Strong expertise of molecular biology and genetics
  • Interested in next-generation sequencing (Illumina, PacBio, Nanopore)
  • Ability to collaboratively establish and run high-quality single-cell service (including SOPs) for researchers, but also for national partners in academia, industry and the clinic
  • Project management and effective communication skills
  • Good mastery of English language
  • Experience with, or minimally interested in microfluidic chips, droplet microfluidics, nano-biotechnology
  • Interested in single-cell biology
  • Interested in tech transfer, Intellectual Property, biotech industry

Appreciated

  • Experience with next-generation sequencing
  • Experience with (droplet) microfluidics
  • Experience with pipetting robots
  • Experience with tissue culture, immunohistochemistry, cryostat
  • Experience with bioinformatics (R, Python)

We offer

  • A stimulating, diverse, international and strong research environment in a world-class academic laboratory with a focus on single-cell genomics, computational biology, Artificial Intelligence, and gene regulation
  • Opportunity to learn state of the art single-cell and sequencing technology
  • Opportunity to drive a large international project on Parkinson’s disease
  • Opportunity to work with an excellent single-cell expertise unit (Suresh Poovathingal)
  • Access to state-of-the-art infrastructure
  • A competitive compensation package based on expertise and experience
  • Open-ended contract

Start date: as soon as possible - the position is available immediately

How to apply?

Please complete the online application procedure and include a detailed CV, a motivation letter describing research interests and previous research experience, and a list of publications.  For more information: please contact stein.aerts@kuleuven.vib.be

https://cbd.vib.be

http://www.aertslab.org

https://cbd.vib.be/careers/training/