Research technician: Genome Editing and Systems Genetics

Leuven VIB-KU Leuven Center for Microbiology

11 Jan 2021

Leuven

VIB-KU Leuven Center for Microbiology

Technical Support

1

About VIB

Basic research in life sciences is VIB’s raison d’être. VIB is an independent research institute where some 1,500 top scientists from Belgium and abroad conduct pioneering basic research. As such, they are pushing the boundaries of what we know about molecular mechanisms and how they rule living organisms such as human beings, animals, plants, and microorganisms. 

Based on a close partnership with five Flemish universities – Ghent University, KU Leuven, University of Antwerp, Vrije Universiteit Brussel, and Hasselt University – and supported by a solid funding program, VIB unites the expertise of all its collaborators and research groups in a single institute.

VIB’s technology transfer activities translate research results into concrete benefits for society such as new diagnostics and therapies and agricultural innovations. These applications are often developed by young start-ups from VIB or through collaborations with other companies. This also leads to additional employment and bridges the gap between scientific research and entrepreneurship.

VIB also engages actively in the public debate on biotechnology by developing and disseminating a wide range of science-based information.

Our institute greatly values diverse standpoints and equality and promotes an inclusive research environment in which everybody, irrespective of nationality, gender, race, and personal beliefs is respected.

VIB‐KU Leuven Center for Microbiology

The VIB-KU Leuven Center for Microbiology is part of the VIB life sciences institute and is embedded within the University of Leuven. The Center aims to combine leading basic microbiology and systems biology research with top technology transfer activities.  

The current research focuses on microbes as a model to study their general biology, cellular physiology, ecology, and evolution, including themes like genetic and epigenetic inheritance, cellular sensing and signaling, biofilms, and the intestinal ecosystem. Apart from being a leader in basic research, the Center is also an important hub for translational research, with emphasis on the beer, wine, bakery, biofuels, and green chemicals industries, as well as human medicine (antifungals, microbiome analysis,…).

Job description

We are looking for highly motivated applicants for the position of research technician in the Genome Editing and Systems Genetics Group (Vonesch lab – VIB-KU Leuven Center for Microbiology). 

You would have a central role in helping to set up the research group and would make original contributions to scientific projects. We develop cutting edge CRISPR technologies for high-throughput precision genome perturbation, and scalable functional genomics and genome-wide technologies that measure molecular and cellular consequences of genetic perturbations. 

We apply these tools to unravel the functional roles of genetic variants in the context of complex traits and synthetic biology. The yeast S. cerevisiae, a model for many basic processes in humans and other biological systems, is our main model system, but we are looking to transfer our technologies to other organisms. Work in the group is highly multidisciplinary across diverse projects and integrates wetlab and computational biology.

Profile

You have a university degree or equivalent training certificate in a relevant field, and significant hands-on experience relevant to the research lines of the group (CRISPR/Cas genome engineering, next-generation sequencing, high-throughput technologies). You have extensive experience in using standard molecular biology and cloning techniques, as well as in microbial cultivation. 

Flexibility, good organizational skills, willingness to learn new skills as projects require, a high level of independence and the ability to work in a multidisciplinary team within a highly collaborative international atmosphere are essential. 

The successful candidate should have excellent verbal and written English communication skills. The working language is English.

Responsibilities

  • Helping to set up the research group.
  • Developing and evaluating new technologies, reagents or experimental protocols, in particular in the fields of next-generation sequencing, CRISPR-based genome editing, and other high-throughput technologies.
  • Working in close collaboration with postdocs and Ph.D. students and providing support to lab members throughout their projects.
  • Training of new group members in methods and protocols used in the lab.
  • Help with general lab organization.

We offer

  • A stimulating, diverse, and international research environment in a young and dynamic team. You will be part of building a new research group with ample opportunities for mentoring and career development.
  • Open-ended contract
  • Access to state-of-the-art infrastructure, including robotics instrumentation and next-generation sequencing facilities
  • A competitive compensation package based on expertise and experience
  • Possibility for further training and education
  • Job is available from April 2021, starting date is negotiable

How to apply?

Interested candidates are asked to apply online.

For more information please contact Dr. Sibylle Vonesch (vonesch.lab@vib.be).

Applications must include a CV, a letter of motivation and the contact details of two referees.