Postdoc position on the role of VPS13C in Lewy Body Diseases

Leuven VIB-KU Leuven Center for Brain & Disease Research

03 Jul 2022

Leuven

VIB-KU Leuven Center for Brain & Disease Research

Wim Annaert Lab

Post-doctoral

1

06 Jul 2022

The VIB-Center for Brain & Disease Research (VIB-CBD) at KU Leuven (Belgium) is a vibrant and international center with a strong focus on major neurodegenerative disease research. The VIB-CBD hosts 14 research groups and 9 expertise units with over 300 neuroscience researchers from almost 40 different nationalities.  Herein, the lab of Membrane Trafficking headed by Prof. Wim Annaert (https://cbd.vib.be/labs/annaert-lab) is urgently looking for a postdoc to continue their ongoing efforts in exploring the role of VPS13C in the context of Lewy Body Diseases. VPS13C is a lipid transfer protein localized in endoplasmic reticulum-lysosome/lipid droplet contact sites. Mutations in the VPS13C gene are linked to early-onset Parkinson’s Disease and Dementia with Lewy Bodies, suggesting underlying common molecular mechanisms. These are investigated in unique patient-derived iPSC-derived human neurons and microglia, combining up-to-date molecular and biochemical technologies, interactomics and advanced imaging, in particular, super-resolution up to single-molecule microscopy and (CL)EM.  

Profile

We seek a young and ambitious postdoctoral fellow with a strong molecular and cell biology background and a keen interest or experience in neurodegenerative disease research. Proficient experience in advanced imaging, including super-resolution microscopy, is of added value. The ability to work in a multidisciplinary research team as well as effective communication and writing skills and a good mastery of the English language are essential for a successful selection.

We offer

  • A stimulating international research environment
  • Access to top state-of-the-art research facilities and infrastructure
  • Competitive salary and benefits
  • Minimally 2-year funding is available but candidates are encouraged to apply for international postdoc fellowships (e.g., EMBO, MSCA, etc.).

Starting date: as soon as possible.

How to apply?

Please use the online application procedure.

Additional required information:

  • Please enclose a motivation letter with a summary of your research experience to your application
  • Please mention the contact details of two references (of which one of your Ph.D. mentors) in the application form

The best-ranked candidates will be invited for an interview.

Profile and selected papers of the Annaert lab can be found on: http://www.vib.be/en/research/...

Further info on VIB-CBD:

VIB values diversity - in backgrounds and in experiences. The institute needs people from all backgrounds and ways of life to help build a thriving scientific environment. VIB is therefore looking for candidates who are not only strong in their own aptitudes but care deeply about supporting each other's growth. VIB's collaborators are people with different strengths, experiences and backgrounds, who share a passion for science that generates impact in science and in society. Diversity not only includes race and gender identity, but also nationality, age, disability status, sexual orientation, religion and many other parts of ones identity. All of VIB's employees' points of view are key to its success, and inclusion is everyone's responsibility.