Postdoc position: Computational genomics of Alzheimer’s disease

Antwerp VIB-UAntwerp Center for Molecular Neurology

16 Sep 2022

Antwerp

VIB-UAntwerp Center for Molecular Neurology

Kristel Sleegers Lab

Post-doctoral

1

The Sleegers lab (Complex Genetics of Alzheimer’s Disease) at the VIB-UAntwerp Center for Molecular Neurology, Belgium, is seeking a highly motivated postdoctoral fellow to work in the field of computational genomics of complex Alzheimer’s disease.

The Sleegers lab is committed to increasing insights into the complex genetics of Alzheimer’s disease and to investigating the translational potential of genetic discovery. We use advanced genomic technologies and genetic-epidemiological methods on human study populations to identify molecular mechanisms that can serve as future targets for early detection, prevention, and treatment. We participate in numerous international networks and consortia, to enhance gene identification, interdisciplinary gene characterization and early biomarker discovery.

The VIB-UAntwerp Center is part of VIB, a Life Sciences institute with colleague-researchers in neuroscience, cancer, biotechnology, structural biology, and immunology amongst others and an extensive set of core facilities and opportunities for technology transfer. The VIB-UAntwerp Center is also embedded within the University of Antwerp. The University of Antwerp is a dynamic, forward-thinking university, offering an innovative academic education to more than 20 000 students; conducting pioneering scientific research and playing an important service-providing role in society with more than 6000 employees from 100 different countries.

Selected references:

  • Cuyvers et al. Lancet Neurology (2015) 14(8):814-822
  • De Roeck et al. Acta Neuropathologica (2018) 135(6):827-837
  • De Roeck et al. Genome Biology (2019) 20(1):239
  • Neumann et al. Molecular Psychiatry (2022) 27:1990-1999
  • Bellenguez, Küçükali et al. Nature Genetics (2022) 54:412-436

Profile

We are seeking a highly motivated, critical and creative individual with a strong interest in computational genomics and Alzheimer’s disease to develop and/or apply computational approaches to large scale genomic or transcriptomic datasets for identification of targets for early detection, prevention or treatment of Alzheimer’s disease.

The candidate should have:

  • a PhD in genetic epidemiology, statistical genetics, bioinformatics or related disciplines
  • scientific excellence and integrity
  • good programming skills, proficiency in Unix/Linux and cluster experience
  • a strong track record in -omics data analysis (short and long read DNA / RNA sequencing, in situ sequencing, single cell data analysis) is a plus 
  •  excellent communication and writing skills in English 

We offer

  • Financial support for at least 2 years. The successful candidate is encouraged to obtain a personal fellowship (Marie-Curie, HFSP, EMBO, or national funding organizations)
  • A versatile and challenging job in a vibrant, world-class research environment operating at an international level
  • Access to state of the art infrastructure and core computing and experimental facilities
  • Dedicated training programs available through VIB and UAntwerp to broaden your expertise and enhance your skill set
  • A strong and dynamic network of international collaborators

As part of the VIB-UAntwerp Center for Molecular Neurology and VIB, the applicant will benefit from established collaborations and access to centralized facilities with expertise in genomics (short and long read sequencing), functional genomics and cell biology, proteomics, cutting-edge microscopy, structural biology, technology development, and bioinformatics.

VIB provides a highly interactive environment and ample training opportunities for its researchers. The VIB-UAntwerp Center for Molecular Neurology is located in the city of Antwerp, the capital of Flanders, offering a culturally and historically rich and ethnically diverse environment.

Starting Date: as soon as possible

How to apply?

You can apply for this job through the online job application platform.

Please include the following document(s):

  • a detailed CV
  • a letter of motivation describing your interests
  • contact details of two referees

For more information contact kristel.sleegers@uantwerpen.vib.be or jobs.cmn@uantwerpen.vib.be

https://sleegerslab.sites.vib.be/

https://uantwerpen.vib.be

The University of Antwerp is a sustainable, family-friendly organization, which invests in its employees’ growth. We encourage diversity and attach great importance to an inclusive working environment and equal opportunities, regardless of gender identity, disability, race, ethnicity, religion or belief, sexual orientation or age. We encourage people from diverse backgrounds and with diverse characteristics to apply.

VIB values diversity - in backgrounds and in experiences. The institute needs people from all backgrounds and ways of life to help build a thriving scientific environment. VIB is therefore looking for candidates who are not only strong in their own aptitudes but care deeply about supporting each other's growth. VIB's collaborators are people with different strengths, experiences and backgrounds, who share a passion for science that generates impact in science and in society. Diversity not only includes race and gender identity, but also nationality, age, disability status, sexual orientation, religion and many other parts of ones identity. All of VIB's employees' points of view are key to its success, and inclusion is everyone's responsibility.